Resumo Os transtornos psiquiátricos possuem grande morbidade entre estudantes universitários da área da saúde. A depressão e ansiedade são os mais frequentes. O artigo se propõe a analisar os diferentes graus da depressão nos cursos da área de saúde e correlacionar esse transtorno ao gênero e à idade. O trabalho foi qualiquantitativo, desenvolvido com os acadêmicos de medicina, enfermagem e odontologia submetidos ao Inventário de Depressão de Beck (BDI). Fizeram parte da amostra 383 acadêmicos; a quantidade de alunos matriculados em medicina foi de 44 (11,62%), odontologia, 94 (24,50%) e enfermagem, 245 (63,87%). Desses, 273 (71,3%) eram mulheres e 110 (28,70%) homens com um intervalo na faixa etária de 26 a 33 anos. Identificou-se que não houve associação entre a variável depressão e gênero; a depressão grave foi constatada em 5,40% dos estudantes de odontologia, 8,60% dos de enfermagem e a depressão moderada a grave em 3,60% dos de medicina. Nota-se pelo BDI que os sintomas depressivos entre estudantes da área da saúde têm-se mostrado superior a outras populações de idade correspondente. A depressão é um fator de risco para a sociedade sendo importante a formulação de políticas de saúde mental, adotando-se medidas de apoio emocional, reestruturação da grade curricular e implementação de atividades psicológicas de autocontrole com criação de grupos de assistência psicológica ao aluno visando a prevenção de transtornos psíquicos nesses futuros profissionais da saúde.

Abstract Psychiatric disorders have great morbidity among university students in the health care area. Depression and anxiety are more common. The article proposes to analyze the different degrees of depression in health care courses and correlate this disorder to gender and age. The work was quantitative and qualitative, developed with student of medicine, nursing and dentistry that were submitted to the Beck Depression Inventory (BDI). 383 scholars were part of the sample; The number of students enrolled in medicine was 44 (11.62%), dentistry 94 (24.50%) and nursing 245 (63.87%). Of these, 273 (71.30%) were women and 110 (28.70%) men with an age range of 26 to 33 years. It was identified that there was no association between depression and the gender variable; severe depression was found in 5.40% of dentistry students, 8.60% of nursing students and moderate to severe depression in 3.60% of medicine students. It is noted by the BDI that depressive symptoms among health care students have shown to be higher than in other populations of the same age. Depression is a risk factor for society and it is important to formulate mental health care policies, adopting measures of emotional support, restructuring curriculum and implementing psychological activities of self-control with the creation of groups of psychological assistance to the students aiming at the prevention of psychic disorders in these future health care professionals.

Resumen Los trastornos psiquiátricos poseen gran morbilidad entre los universitarios del área de la salud. La depresión y la ansiedad son los más frecuentes. El artículo se propone analizar los diferentes grados de la depresión en los cursos del área de salud y correlacionar ese trastorno al género y a la edad. El trabajo fue cuantitativo y cualitativo, desarrollado con los académicos de medicina, enfermería y odontología sometidos al Inventario de Depresión de Beck (BDI). La muestra incluyó a 383 académicos; la cantidad de alumnos matriculados en medicina fue de 44 (11,62%), odontología 94 (24,50%) y enfermería 245 (63,87%). De ellos, 273 (71,30%) eran mujeres y 110 (28,70%) hombres con un rango de edad de 26 a 33 años. Se identificó que no hubo asociación entre la variable depresión y género; la depresión severa fue constatada en el 5,40% de los estudiantes de odontología, el 8,60% de los de enfermería y depresión moderada a severa en el 3,60% de los de medicina. Se observa por el BDI que los síntomas depresivos entre estudiantes del área de la salud se han mostrado superiores a otras poblaciones de edad correspondiente. La depresión es un factor de riesgo para la sociedad siendo importante la formulación de políticas de salud mental, adoptando medidas de apoyo emocional, reestructuración de la red curricular e implementación de actividades psicológicas de autocontrol con creación de grupos de asistencia psicológica al alumno visando la prevención de trastornos psíquicos en estos futuros profesionales de la salud.

Abstract Purpose: To evaluate the effect of aqueous extract of Baccharis trimera leaves on the proliferative capacity of the liver after partial hepatectomy (PH) in rats. Methods: Twenty Wistar rats weighing between 300 and 450g were divided into two groups: control (HP) and test (HP100-rats that received the aqueous extract of Baccharis trimera for four days at a dose of 100 mg / kg / day). On the fifth day, animals from both groups underwent resection of 70% of the liver. Twenty-four hours later, they were sacrificed and the remnant liver was removed and prepared for studied through PCNA immunohistochemistry. Data analysis for comparison between the two groups was made through the non-parametric statistical test Mann-Whitney test. Results: In all the animals studied was found most abundant nuclear immunostaining positive hepatocytes interlobular located in regions of the liver. Quantitative analysis of PCNA-positive cells revealed positivity rate significantly higher mean (p = 0.02) in HP100 group (77.1 ± 13.6) compared to the HP group (45.8 ± 12.9). Conclusion: DAdministration of aqueous extract of the leaves of Baccharis trimera 100 mg/kg of animal has a significant positive effect on liver regeneration in rats, 24 hours after hepatectomy (70%).

ABSTRACT PURPOSE: To assess the effect of aqueous extract of Peumus Boldus (AEPB) on the liver proliferative response after parcial hepatectomy of 70% (PH) in rodents. METHODS: Twenty Wistar rats were divided in two groups: AEPB100 (whose rats received 100mg/Kg of AEPB, once a day, orally, in 4 days prior to the first surgical procedure) and Vehicle (whose rats were treated similarly with distilled water). Both groups underwent PH. After 24 hours the remaining livers were removed for studying the proliferation of hepatocytes by Ki-67 and 2mL of blood were collected for serological assessment: cholesterol, glucose, triglycerides, aspartate aminotransferase, alanine aminotransferase, alkaline phosphatase, and total, direct and indirect bilirubin. All data were analyzed by Gaussian distribution. Statistically significant differences between mean values were analyzed using T Student's test. Non-Gaussian data were analyzed using Mann-Whitney's test. RESULTS: The liver of all these rats presented positive staining of Ki-67, indicating liver proliferation. Laboratory results showed no significant difference in serum values between the analyzed groups. The analysis of Ki-67 was significantly more positive in AEPB100 group than in Vehicle group. CONCLUSION: Aqueous extract of Peumus Boldus acute administration exerts significant positive effect on liver regeneration after 24h in rats that underwent parcial hepatectomy, while maintaining unchanged hepatic function.